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Integrated analysis reveals critical cisplatin-resistance regulators E2F7 contributed to tumor progression and metastasis in lung adenocarcinoma

2024-01-22

Abstract excerpt

Cisplatin resistance remains a significant barrier in treating lung adenocarcinoma (LUAD). While the search for predictive biomarkers in LUAD prognosis has seldom focused on cisplatin resistance genes. In this study, we analyzed 181 cisplatin resistance genes from LUAD-related cell lines RNA sequences data using the TCGA and GEO databases, identifying two pivotal genes, E2F7 and FAM83A. Utilizing these genes, we e...

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Literature Corpus work
79de6d8e-1ee9-5b78-80cf-a17b47b02061
DOI
10.21203/rs.3.rs-3877484/v1
Open publication

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Integrated analysis reveals critical cisplatin-resistance regulators E2F7 contributed to tumor progression and metastasis in lung adenocarcinomaDOI 10.21203/rs.3.rs-3877484/v1
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