Article

Elexacaftor/ivacaftor/tezacaftor effect on microbial density and the microbiome composition.

2022-08-09

Abstract excerpt

Introduction Previous generations of CFTR modulation have been shown to temporarily decrease the frequency of culture positivity of P. aeruginosa and other respiratory pathogens. Recently, a three-drug combination Trikafta (elexacaftor/ivacaftor/tezacaftor) was approved for individuals with at least one F508del mutation. There is limited data on the effect of CFTR modulators on bacterial density and CF microbiome...

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Literature Corpus work: 7b9a8e60-e442-5a15-bb9f-feb21f5afbd6
DOI: 10.22541/au.166005200.02022549/v1

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