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Article

Metagenomic Next-Generation Sequencing for Pathogen Detection and Transcriptomic Analysis in Pediatric Central Nervous System Infections

6 Mar 2021

Abstract excerpt

BACKGROUND: Pediatric central nervous system (CNS) infections are potentially life-threatening and may incur significant morbidity. Identifying a pathogen is important, both in terms of guiding therapeutic management and in characterizing prognosis. Usual care testing by culture and polymerase chain reaction is often unable to identify a pathogen. We examined the systematic application of metagenomic...

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Bacterial Infections and Vaccines
Genomics and Phylogenetic Studies
Infectious Encephalopathies and Encephalitis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34104666
DOI: 10.1093/ofid/ofab104

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