Article

Hepatitis B virus integrations promote EMT via upregulation of PAK3 expression in HepG2.2.15 cells

2026-06-28

Abstract excerpt

<title>Abstract</title> <p> Hepatitis B virus (HBV) integration causes hepatocellular carcinoma (HCC); however, the specific molecular mechanisms remain to be fully elucidated. Epithelial-mesenchymal transition (EMT) is essential for tumor metastasis, and p21-activated kinase 3 (PAK3) promotes EMT. Results of the present study revealed that PAK3 was highly expressed in liver tumor tissues compared with paired he...

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Literature Corpus work: 7b70f451-b3eb-507c-a064-619ff7aad3fc
DOI: 10.21203/rs.3.rs-9715959/v1

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