Article

Formation of an Immunosuppressive Spatial Network Between Tumor-Associated SPP1⁺ Macrophages and Fibroblasts in Cervical Cancer with Distant Metastasis

2025-10-16

Abstract excerpt

<title>Abstract</title> <p>Background Cervical cancer (CC) is a common malignancy among women worldwide, and distant metastasis is the main cause of treatment failure and mortality. Immune cells, stromal cells, and their interactive networks within the tumor microenvironment (TME) play a key role in the development, colonization, and immune escape in metastasis. For example, tumor-associated macrophages (TAMs) ar...

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Literature Corpus work: 7b65b1c0-6ba8-514e-92c6-786fa44ce6d1
DOI: 10.21203/rs.3.rs-7748094/v1

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