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Gut bacterial supernatants modulate neuronal survival and neuron–glia morphology in a hippocampal culture model of Parkinson’s disease

2026-08-26

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Parkinson's disease (PD) is characterised by the accumulation and spread of α-synuclein (α-syn). Increasing evidence suggests that alterations in the gut microbiome occur early in PD and that microbiome-derived factors may contribute to disease pathogenesis through the gut–brain axis. <bold>Methods:</bold> Supernatants (SNs) from 16 bacterial strains were c...

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Literature Corpus work
7b53f318-c848-5fc8-8661-415dbaa40ba7
DOI
10.21203/rs.3.rs-10729381/v1
Open publication

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Gut bacterial supernatants modulate neuronal survival and neuron–glia morphology in a hippocampal culture model of Parkinson’s diseaseDOI 10.21203/rs.3.rs-10729381/v1
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