Article

Gut bacteria impact host uric acid burden and its association with atherosclerosis

2022-12-13

Abstract excerpt

Humans with metabolic and inflammatory diseases, including atherosclerosis harbor dysbiotic gut communities. However, the microbes and microbial pathways that influence disease progression remain largely undefined. Here, we show that variation in atherosclerosis burden is in part driven by the gut microbiota and it is associated with circulating levels of the proinflammatory molecule uric acid both in mice and hum...

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Literature Corpus work: 7b3be82b-2f03-5447-b4c9-0687da010aa0
DOI: 10.1101/2022.12.12.520169

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