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Article

Ultrasonic potentiation of ketamine neuromodulation

2026-08-04

Abstract excerpt

The psychiatric utility of ketamine is limited by its dissociative and systemic side effects. Recently, to enable precision ketamine pharmacotherapy, we introduced SonoKet, ketamine-loaded acoustically activatable liposomes that enable focused ultrasound (FUS)-targeted ketamine delivery to millimeter-sized brain regions. In initial studies, we observed that SonoKet uncaging targeted ketamine to the ultrasound-trea...

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Literature Corpus work
7b21569e-f5ec-58da-a82b-fc33a6b2f4e9
DOI
10.64898/2026.07.29.741494
Open publication

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