Article

Low Intensity Ultrasound Neuromodulation for the treatment of Major Depressive Disorder: Systematic Review and Meta‑Analysis of Randomized Controlled Trials

2025-11-24

Abstract excerpt

<title>Abstract</title> <p>Background Major depressive disorder (MDD) affects over 264 million individuals globally, yet about one‑third of patients fail to achieve remission with conventional therapies. Low‑intensity ultrasound neuromodulation (LIUN), which includes low‑intensity focused ultrasound (LIFU) and transcranial pulse stimulation (TPS), offers millimetre‑scale targeting and the ability to reach deep li...

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Literature Corpus work: 5c79c6ac-c923-5624-b5a9-7a7888fa1558
DOI: 10.21203/rs.3.rs-7930997/v1

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