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Integrated Multi-Omics Analysis Reveals Folate Metabolism Related Genes as Prognostic Markers and Therapeutic Targets in Clear Cell Renal Cell Carcinoma

2026-03-27

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<title>Abstract</title> <p>Background Clear cell renal cell carcinoma (ccRCC) is an aggressive tumor with high metastatic potential and therapeutic resistance, yet the role of folate metabolism in its pathogenesis and immune evasion remains unclear. This study aims to develop and validate a folate metabolism related gene (FMRG) scoring system to stratify patients by prognostic risk and immune phenotypes, and to...

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Literature Corpus work
7b0076a5-a33b-5125-8641-d2735f28a869
DOI
10.21203/rs.3.rs-9129596/v1
Open publication

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Integrated Multi-Omics Analysis Reveals Folate Metabolism Related Genes as Prognostic Markers and Therapeutic Targets in Clear Cell Renal Cell CarcinomaDOI 10.21203/rs.3.rs-9129596/v1
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