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Development of a polyamine gene expression score for predicting prognosis and treatment response in clear cell renal cell carcinoma

25 Nov 2022

Abstract excerpt

Backgrounds: Polyamine metabolism (PM) is closely related to the tumor microenvironment (TME) and is involved in antitumor immunity. Clear cell renal cell carcinoma (ccRCC) not only has high immunogenicity but also has significant metabolic changes. However, the role of PM in the immune microenvironment of ccRCC remains unclear. This study aimed to reveal the prognostic value of PM-related genes (PMRGs)...

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PMID: 36505496
DOI: 10.3389/fimmu.2022.1048204

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