Back to search

Article

The nasal symbiont Staphylococcus epidermidis shapes the cellular environment to decrease expression of SARS-CoV-2 entry factors in nasal epithelium

2021-02-18

Abstract excerpt

<title>Abstract</title> <p>Background Emerging evidence indicates that severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) targets the human nasal epithelium via the principal entry factors angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2), which are highly expressed in the nasal epithelium. However, little is known about suppressive biologics against SARS-CoV-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7a69ff33-3500-5c27-8da4-d5852fa90d1a
DOI
10.21203/rs.3.rs-208802/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The nasal symbiont Staphylococcus epidermidis shapes the cellular environment to decrease expression of SARS-CoV-2 entry factors in nasal epitheliumDOI 10.21203/rs.3.rs-208802/v1
The Nasal Symbiont <i>Staphylococcus Epidermidis</i> Restricts the Transcription of SARS-CoV-2 Entry Factors in Human Nasal EpitheliumSemantic proximity
Nasal commensal, <i>Staphylococcus epidermidis</i> shapes the mucosal environment to prevent influenza virus invasion through Serpine1 inductionSemantic proximity
Expression Pattern of the SARS-CoV-2 Entry Genes ACE2 and TMPRSS2 in the Respiratory TractSemantic proximity
Nasopharyngeal Expression of Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Serine Protease 2 (TMPRSS2) in Children Compared to Adults Within Family Clusters Exposed to COVID-19Semantic proximity
Differential expression of Angiotensin-Converting Enzyme 2 in Nasal Tissue of Patients with Chronic Rhinosinusitis with Nasal PolypsSemantic proximity
Early Reduction of SARS-CoV-2 Replication in Bronchial Epithelium by Kinin B<sub>2</sub> Receptor AntagonismSemantic proximity
Comparative Evaluation of Nasal and Small Intestine Expression of ACE2, TMPRSS2 and ACE1 and in Children and in AdultsSemantic proximity
Expression of the SARS-CoV-2 <i>ACE2</i> Receptor in the Human Airway EpitheliumSemantic proximity
The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epitheliaSemantic proximity
Age- and airway disease related gene expression patterns of key SARS-CoV-2 entry factors in human nasal epitheliaSemantic proximity
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genesSemantic proximity
Human Surfactant Protein A Alleviates SARS-CoV-2 Infectivity in Human Lung Epithelial CellsSemantic proximity
Select a neighboring publication to make it the new centre.