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A Cross-Study Multi-Organ Cell Atlas of <i>Macaca fascicularis</i> Informed by Human Foundation Model Annotation: A Resource for Translational Target Assessment

2026-03-19

Abstract excerpt

Non-human primates (NHPs), particularly Macaca fascicularis (cynomolgus macaque), represent an essential model for preclinical assessment of biologics due to their high genetic and physiological similarity to humans. However, mounting regulatory pressure to reduce NHP use and the lack of a unified, well-annotated single-cell atlas currently limits both target qualification and mechanistic interpretation of toxici...

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Literature Corpus work
7a676b2c-138c-5561-943a-f52e8938423b
DOI
10.64898/2026.03.17.711997
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A Cross-Study Multi-Organ Cell Atlas of <i>Macaca fascicularis</i> Informed by Human Foundation Model Annotation: A Resource for Translational Target AssessmentDOI 10.64898/2026.03.17.711997
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