Article

Prevalence, Production and the Role of <i>Staphylococcus aureus</i> Superantigens in Cystic Fibrosis Lung Disease

2025-05-12

Abstract excerpt

<h4>ABSTRACT</h4> Staphylococcus aureus (SA), the most common cystic fibrosis (CF) lung pathogen, is uniquely capable of producing superantigen (SAg) exotoxins, which are the most potent activators of the immune system. Although the proinflammatory roles of SA-SAgs is well-established, their role in the immunopathogenesis of CF lung disease is unexplored. Herein, we demonstrate that 60-80% of pediatric and adult...

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Literature Corpus work: 7a3c3bd0-88b6-5847-b5d0-b6782317cf82
DOI: 10.1101/2025.05.07.652658

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