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Article

Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide.

International journal of radiation oncology, biology, physics - 1 Nov 2020

Rahman Rifaquat, Trippa Lorenzo, Alden Stephanie, Fell Geoffrey, Abbasi Taher, Mundkur Yatin, Singh Neeraj K, Talawdekar Anay, Husain Zakir, Vali Shireen, Ligon Keith L, Wen Patrick Y, Alexander Brian M

Abstract excerpt

PURPOSE: Precision medicine has been most successful in targeting single mutations, but personalized medicine using broader genomic tumor profiles for individual patients is less well developed. We evaluate a genomics-informed computational biology model (CBM) to predict outcomes from standard treatments and to suggest novel therapy recommendations in glioblastoma (GBM). METHODS AND MATERIALS: In this...

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Identifiers

PMID: 32417407
DOI: 10.1016/j.ijrobp.2020.05.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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