Article

Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

2021-07-06

Abstract excerpt

<h4>ABSTRACT</h4> Alterations to the balance between excitation and inhibition (E/I ratio) are postulated to underlie behavioral phenotypes in autism spectrum disorder (ASD) patients and mouse models. However, in wild type mice the E/I ratio is not constant, but instead oscillates across the 24h day. Therefore, we tested whether the E/I oscillation, rather than the overall E/I ratio, is disrupted in two ASD-relat...

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Literature Corpus work: 79c15305-0e02-5c19-be5a-c48b87746f4d
DOI: 10.1101/2021.07.05.451213

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