Article

The orchestrated cellular and molecular responses of the kidney to endotoxin define the sepsis timeline

2020-05-30

Abstract excerpt

Clinical sepsis is a highly dynamic state that progresses at variable rates and has life-threatening consequences. Staging patients along the sepsis timeline requires a thorough knowledge of the evolution of cellular and molecular events at the tissue level. Here, we investigated the kidney, an organ central to the pathophysiology of sepsis. Single cell RNA sequencing revealed the involvement of various cell popul...

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Identifiers and source

Literature Corpus work: 7964a11d-cf18-59cb-9bea-c27ede54c7fb
DOI: 10.1101/2020.05.27.118620

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