Article

New developments in chondrocyte ER-stress and related diseases

2020-04-24

Abstract excerpt

Cartilage comprises a single cell type, the chondrocyte, embedded in a highly complex extracellular matrix. Disruption to the cartilage growth plate leads to reduced bone growth and results in a clinically diverse group of conditions known as genetic skeletal diseases (GSDs). Similarly, long-term degradation of articular cartilage can lead to osteoarthritis (OA), a disease characterised by joint pain and stiffness...

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Literature Corpus work: 794f2cda-36a5-5632-a205-a2705467d4cf
DOI: 10.12688/f1000research.22275.1

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