Article

Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell depleting agents

2022-04-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Administration of plasma therapy may contribute to viral control and survival of COVID-19 patients receiving B-cell depleting agents that hinder the endogenous humoral response. However, little is known on the impact of anti-CD20 pre-exposition and the use of different sources of plasma (convalescent versus vaccinated) on the kinetics of SARS-CoV-2-specific antibodies and vira...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 794c1d1f-1f37-5133-9e7b-51f768504c01
DOI: 10.1101/2022.04.24.22274200

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell depleting agentsDOI 10.1101/2022.04.24.22274200Read

Functional Antibodies in COVID-19 Convalescent PlasmaSemantic proximity Read

Anti-SARS-CoV-2 antibody containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19 via increased neutralizing antibody activity – a randomized clinical trialSemantic proximity Read

Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patientsSemantic proximity Read

Distinct Patterns of Humoral and Cellular Immune Responses Following SARS-CoV-2 mRNA Vaccination in Patients With Immune-Mediated Neurological Disorders on Anti-CD20 Therapy: A Prospective Cohort StudySemantic proximity Read

A Role for Nucleocapsid-Specific Antibody Function in COVID-19 Convalescent Plasma TherapySemantic proximity Read

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor populationSemantic proximity Read

Vaccination of COVID-19 Convalescent Plasma Donors Increases Binding and Neutralizing Antibodies Against SARS-CoV-2 VariantsSemantic proximity Read

Decline of humoral responses against SARS-CoV-2 Spike in convalescent individualsSemantic proximity Read

COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic reviewSemantic proximity Read

Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearanceSemantic proximity Read

<i>de Novo</i> Sequencing of Antibodies for Identification of Neutralizing Antibodies in Human Plasma Post SARS-CoV-2 VaccinationSemantic proximity Read

Year-long COVID-19 infection reveals within-host evolution of SARS-CoV-2 in a patient with B cell depletionSemantic proximity Read