Article

Distinct Patterns of Humoral and Cellular Immune Responses Following SARS-CoV-2 mRNA Vaccination in Patients With Immune-Mediated Neurological Disorders on Anti-CD20 Therapy: A Prospective Cohort Study

2021-09-15

Abstract excerpt

Background: Patients with neuroimmunological disorders on anti-CD20 therapy are at increased risk of severe COVID-19. However, little is known about SARS-CoV-2 vaccine efficacy in this cohort. In particular, the impact of B cell depletion on humoral and cellular immune responses to SARS-CoV-2 vaccination remains poorly defined. No study has addressed vaccine responses to the SARS-CoV-2 delta variant in immunocompr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 306b1274-ed8d-58d7-b6d1-d4cc883fa53c
DOI: 10.2139/ssrn.3924204

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct Patterns of Humoral and Cellular Immune Responses Following SARS-CoV-2 mRNA Vaccination in Patients With Immune-Mediated Neurological Disorders on Anti-CD20 Therapy: A Prospective Cohort StudyDOI 10.2139/ssrn.3924204Read

SARS-CoV-2 mRNA Vaccination Induces an Antigen-Specific T Cell Response Correlating with Plasma Interferon-Gamma in B Cell Depleted PatientsSemantic proximity Read

Cellular and Humoral Responses to SARS-CoV-2 Vaccination in Immunosuppressed PatientsSemantic proximity Read

Cellular and humoral responses to SARS-CoV-2 vaccination in immunosuppressed patientsSemantic proximity Read

Altered cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapySemantic proximity Read

Evaluation of Humoral and Cellular Immune Responses to the SARS-CoV-2 Vaccine in Patients With Common Variable Immunodeficiency Phenotype and Patient Receiving B-Cell Depletion Therapy.Semantic proximity Read

Cellular immune response to SARS-CoV-2 infection in humans: a systematic reviewSemantic proximity Read

Discrete Immune Response Signature to SARS-CoV-2 mRNA Vaccination Versus InfectionSemantic proximity Read

Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell depleting agentsSemantic proximity Read

Patients treated with anti-CD20 therapy can mount robust T cell responses to mRNA-based COVID-19 vaccinesSemantic proximity Read

Role of antiviral CD8+ T cell immunity to SARS-CoV-2 infection and vaccinationSemantic proximity Read

A review of leading COVID-19 vaccines, the quest for immune protection, and its key challenges. Part 3: Covid-19 vaccines – Key challenges and translational scienceSemantic proximity Read

Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapySemantic proximity Read