Article

Expressing the pro-apoptotic Reaper protein via insertion into the structural open reading frame of Sindbis virus reduces the ability to infect <i>Aedes aegypti</i> mosquitoes

2022-01-14

Abstract excerpt

<h4>ABSTRACT</h4> Arboviruses continue to threaten a significant portion of the human population, and a better understanding is needed of the determinants of successful arbovirus infection of arthropod vectors. Avoiding apoptosis has been shown to be one such determinant. Previous work showed that a Sindbis virus (SINV) construct called MRE/rpr that expresses the pro-apoptotic protein Reaper via a duplicated subg...

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Literature Corpus work: 7904b7d0-ac2b-5517-b63a-7cad25a6ac55
DOI: 10.1101/2022.01.13.476239

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Expressing the pro-apoptotic Reaper protein via insertion into the structural open reading frame of Sindbis virus reduces the ability to infect <i>Aedes aegypti</i> mosquitoesDOI 10.1101/2022.01.13.476239Read

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