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Mosquito transgenerational antiviral immunity is mediated by vertical transfer of virus DNA sequences and RNAi

30 Nov 2023

Abstract excerpt

Mosquitoes are important vectors for transmission of many viruses of public and veterinary health concern. These viruses most commonly have an RNA genome and infect mosquitoes for life. The principal mosquito antiviral response is the RNAi system which destroys virus RNA. Here, we confirm an earlier study that Aedes aegypti mosquitoes infected with positive-stranded RNA arboviruses can transmit specific immunity...

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PMID: 38155780
DOI: 10.1016/j.isci.2023.108598

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