Article

ALDH1A1+ cells are endometrial progenitors contributing to regeneration and endometriosis

2025-07-08

Abstract excerpt

<title>Abstract</title> <p>Endometrial stem cells and their regenerative properties are implicated in the pathogenesis of endometriosis. Using single-cell RNA sequencing of the adult mouse endometrium, we identified a sub-population of aldehyde dehydrogenase 1a1+ (Aldh1a1+) stem-like cells that co-express stemness genes (Lgr5 and Axin2) and lack proliferative markers (Top2a and Mki67). Using an Aldh1a1cre/ERT2; R...

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Literature Corpus work: 78dd6833-e9d3-5dcc-95fb-2ea09d82a9f1
DOI: 10.21203/rs.3.rs-6831916/v1

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