Article

Integrative plasma lipidomics and proteomics profiling to decipher potential biomarkers of dilated cardiomyopathy

2025-04-16

Abstract excerpt

<h4>Background</h4> Dilated cardiomyopathy (DCM), primarily characterised by left ventricular dilatation and systolic dysfunction, is one of the leading causes of heart failure and requires a critical clinical investigative strategy. However, conventional imaging techniques such as echocardiography and MRI, along with some classical CVD markers (NTproBNP, cTnT), fall short in diagnosing DCM-specific phenotypes. T...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 78cb0f2b-0619-59ef-9374-f03d9a2b0d65
DOI: 10.1101/2025.04.13.648582

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrative plasma lipidomics and proteomics profiling to decipher potential biomarkers of dilated cardiomyopathyDOI 10.1101/2025.04.13.648582Read

Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy.Semantic proximity Read

Screening of Lipid Metabolism-Related Gene Diagnostic Signature for Patients With Dilated CardiomyopathySemantic proximity Read

Where genome meets phenome: rationale for integrating genetic and protein biomarkers in the diagnosis and management of dilated cardiomyopathy and heart failure.Semantic proximity Read

Proteomic Characterisation of Heart Failure Reveals a Unique Molecular Phenotype for Hypertrophic CardiomyopathySemantic proximity Read

Identifying the Oxidative Stress-Related Diagnostic Biomarkers in Dilated Cardiomyopathy by Bioinformatics AnalysisSemantic proximity Read

Multiomics Analysis of Transcriptome, Epigenome, and Genome Uncovers Putative Mechanisms for Dilated Cardiomyopathy.Semantic proximity Read

A Unique Glycerophospholipid Metabolism Profile of Dilated Cardiomyopathy with Predictive valueSemantic proximity Read

Diagnostic biomarkers of dilated cardiomyopathy.Semantic proximity Read

Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathySemantic proximity Read

Novel insights into potential therapeutic targets and biomarkers using integrated multi- <i>omics</i> approaches for dilated and ischemic cardiomyopathiesSemantic proximity Read

Phenotypic clustering of dilated cardiomyopathy patients highlights important pathophysiological differences.Semantic proximity Read

Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformaticsSemantic proximity Read