Article
Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy.
PloS one - 20 Jan 2011
Sysi-Aho Marko, Koikkalainen Juha, Seppänen-Laakso Tuulikki, Kaartinen Maija, Kuusisto Johanna, Peuhkurinen Keijo, Kärkkäinen Satu, Antila Margareta, Lauerma Kirsi, Reissell Eeva, Jurkko Raija, Lötjönen Jyrki, Heliö Tiina, Orešič Matej
Abstract excerpt
Dilated cardiomyopathy (DCM), characterized by left ventricular dilatation and systolic dysfunction, constitutes a significant cause for heart failure, sudden cardiac death or need for heart transplantation. Lamin A/C gene (LMNA) on chromosome 1p12 is the most significant disease gene causing DCM and has been reported to cause 7-9% of DCM leading to cardiac transplantation. We have previously performed cardiac...
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