Article

Past–future information bottleneck framework for simultaneously sampling biomolecular reaction coordinate, thermodynamics and kinetics

2018-12-28

Abstract excerpt

The ability to rapidly learn from high-dimensional data to make reliable bets about the future outcomes is crucial in many contexts. This could be a fly avoiding predators, or the retina processing gigabytes of data almost instantaneously to guide complex human actions. In this work we draw parallels between such tasks, and the efficient sampling of complex biomolecules with hundreds of thousands of atoms. For thi...

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Identifiers and source

Literature Corpus work: 78b28bff-9647-54b3-8e27-913d0dfdd6ff
DOI: 10.1101/507822

Open publication

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