Article
What do molecules do when we are not looking? State sequence analysis for stochastic chemical systems.
Journal of the Royal Society, Interface - 7 Dec 2012
Levin Pavel, Lefebvre Jérémie, Perkins Theodore J
Abstract excerpt
Many biomolecular systems depend on orderly sequences of chemical transformations or reactions. Yet, the dynamics of single molecules or small-copy-number molecular systems are significantly stochastic. Here, we propose state sequence analysis--a new approach for predicting or visualizing the behaviour of stochastic molecular systems by computing maximum probability state sequences, based on initial conditions or...
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