Article

Characterizing the tumor microenvironment of metastatic ovarian cancer by single cell transcriptomics

2020-02-12

Abstract excerpt

Epithelial ovarian cancer is a highly heterogenous, metastatic and lethal disease. The presence of CD8 + T cells within ovarian tumors is positively associated with overall patient survival. Determining if a patient has T cells that respond to immunotherapies, their characteristics and how they can be manipulated to target cancer cells is an area of intense investigation in cancer therapy. This study determines t...

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Literature Corpus work: 78a8cfb5-cb0f-5e0b-9143-2ad601152ca7
DOI: 10.1101/2020.02.11.944561

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