Article

CDC20 is a potential target gene to inhibit the tumorigenesis of MDCK cells

2022-12-10

Abstract excerpt

MDCK is the main cell line for influenza vaccine production. Previous studies have reported that MDCK cells have tumorigenic ability in nude mice. Although complete cell lysis can be ensured during vaccine production, more caution is needed in vaccine production for human use. Therefore, the use of gene editing technology to establish cells that cannot form tumors can significantly improve the biosafety of influen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 786c4d49-72ca-5fa7-959a-bbb69ba6ee45
DOI: 10.22541/au.167069039.95224014/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CDC20 is a potential target gene to inhibit the tumorigenesis of MDCK cellsDOI 10.22541/au.167069039.95224014/v1Read

A compendium of adenovirus genetic modifications for enhanced replication, oncolysis, and tumor immunosurveillance in cancer therapy.Semantic proximity Read

The Screening and Mechanism of Influenza-Virus Sensitive MDCK Cell Lines for Influenza Vaccine ProductionSemantic proximity Read

The Antiviral and Antitumor Effects of Defective Interfering Particles/Genomes and Their MechanismsSemantic proximity Read

High Yield Production of Influenza Virus in Madin Darby Canine Kidney (MDCK) Cells with Stable Knockdown of IRF7Semantic proximity Read

Establishment and characterization of a new mouse gastric carcino-ma cell line, MCCSemantic proximity Read

A novel tumor-targeted interferon-alpha/-beta receptor 1 antagonist increases replication of oncolytic vesicular stomatitis virus in a mouse mesothelioma modelSemantic proximity Read

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.Semantic proximity Read

Modeling the proteome of a Marek's disease transformed cell line: a natural animal model for CD30 overexpressing lymphomasSemantic proximity Read

Cloning Genes Encoding MHC Class II-Restricted Antigens: Mutated CDC27 as a Tumor AntigenSemantic proximity Read

Gene function analysis using the chicken B-cell line DT40.Semantic proximity Read

Adenovirus i-leader truncation bioselected against cancer-associated fibroblasts to overcome tumor stromal barriers.Semantic proximity Read

Impaired Lymphocytes Development and Xenotransplantation of Gastrointestinal Tumor Cells in Prkdc-Null SCID Zebrafish Model.Semantic proximity Read