Article

Evaluation of the Irritation and Sensitization Potential of Medical-grade Norway Spruce (<i>Picea abies</i>) Resin Salve: Single-Blind Modified Draize Repeat Insult Patch Test in Healthy Volunteers

2025-02-23

Abstract excerpt

<h4>Background</h4> Abilar® is a wound salve containing 10 % medical-grade Norway spruce ( Picea abies ) resin, known for its antimicrobial and wound-healing properties. However, isolated reports of allergic contact dermatitis have raised concerns regarding its cutaneous safety profile. Given the increasing use of Picea abies resin-based products, it is important to evaluate any potential for skin irritation and s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 780fe906-72a6-5ef4-a81a-caef19452b9c
DOI: 10.1101/2025.02.20.25320648

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evaluation of the Irritation and Sensitization Potential of Medical-grade Norway Spruce (<i>Picea abies</i>) Resin Salve: Single-Blind Modified Draize Repeat Insult Patch Test in Healthy VolunteersDOI 10.1101/2025.02.20.25320648Read

Irritation Potential and Acute Efficacy of Topically Applied Niagen® (Niacinamide Riboside Chloride)Semantic proximity Read

<span style="mso-bidi-font-style: italic;">In Vitro Skin Models for Skin Sensitisation: Challenges and Future DirectionsSemantic proximity Read

Annoying Skin Reaction Among The Medical Staff Using Personal Protective Equipment During COVID-19Semantic proximity Read

Phenotypic Characteristics of Occupational Asthma Caused by Persulfate Salts in Hairdressers: A Multicenter Cohort Study.Semantic proximity Read

Adaptation of the KeratinoSens™ skin sensitization test to animal-product-free cell cultureSemantic proximity Read

A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness AnalysisSemantic proximity Read

Anchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing dataSemantic proximity Read

When Genes Meet Gels: Computational Immunogenetics of Dermal Fillers and Stratified Risk of Immune and Fibrotic Reactions across Compositions and Genotypes.Semantic proximity Read

Photochemical Skin Injury Caused by Highly Oxygenated Compounds of Sosnovsky’s HogweedSemantic proximity Read

Commercial Silver-based Dressings: In vitro and Clinical Studies in Treatment of Chronic and Burn WoundsSemantic proximity Read

Mitigating Ammonia-Triggered Inflammation in Human Skin Model: Modulatory Effects of a Purified Water Wipe FormulationSemantic proximity Read

A review on natural products as wood protectantSemantic proximity Read