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Article

Adaptation of the KeratinoSens™ skin sensitization test to animal-product-free cell culture

1 Jan 2017

Abstract excerpt

Skin sensitization is the process by which a substance induces an allergic reaction following skin contact. The process has been described as an adverse outcome pathway (AOP), including several key events, from skin penetration and covalent protein binding, to keratinocyte activation, dendritic cell activation and T-lymphocyte proliferation. The in vitro assay KeratinoSens™ measures the activation of...

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Share to Contact Dermatitis and Allergies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28403479
DOI: 10.14573/altex.1701311

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