Article

CACNA2D4 variants are associated with exertional heat stroke susceptibility

2026-01-30

Abstract excerpt

Exertional Heat Stroke (EHS) is a life-threatening disease defined by severe hyperthermia and sudden neurological dysfunction in healthy individuals exposed to intense physical exercise. As is the case with some forms of malignant hyperthermia, mutations in genes involved in skeletal muscle contraction could predispose some patients to EHS. However, the genetic basis of EHS remains poorly documented. Here we ident...

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Literature Corpus work: 778e9799-12dc-551b-8727-eead0da37411
DOI: 10.64898/2026.01.28.702251

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