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Surrogate virus neutralisation test based on nanoluciferase-tagged antigens to quantify inhibitory antibodies against SARS-CoV-2 and characterise Omicron-specific reactivity

2023-10-10

Abstract excerpt

<h4>ABSTRACT</h4> Virus-specific antibodies are important determinants of protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While regarded as the gold standard for detecting functional antibodies, conventional virus neutralisation tests (VNT) or pseudotyped virus neutralisation tests (pVNT) require biosafety level 2 or 3 facilities. Alternatively, the virus-free surrogate vi...

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Literature Corpus work
778e85d9-b9dd-5aa6-b668-f74436bf3a14
DOI
10.1101/2023.10.10.23296792
Open publication

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Surrogate virus neutralisation test based on nanoluciferase-tagged antigens to quantify inhibitory antibodies against SARS-CoV-2 and characterise Omicron-specific reactivityDOI 10.1101/2023.10.10.23296792
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