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A surrogate virus neutralization test to quantify antibody-mediated inhibition of SARS-CoV-2 in finger stick dried blood spot samples

2021-02-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The spike protein of SARS-CoV-2 engages the human angiotensin-converting enzyme 2 (ACE2) receptor to enter host cells, and neutralizing antibodies are effective at blocking this interaction to prevent infection. Widespread application of this important marker of protective immunity is limited by logistical and technical challenges associated with live virus methods and venous...

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Literature Corpus work
2586d888-6e7f-58d2-a3aa-179db6a2ea9f
DOI
10.1101/2021.02.14.21251709
Open publication

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A surrogate virus neutralization test to quantify antibody-mediated inhibition of SARS-CoV-2 in finger stick dried blood spot samplesDOI 10.1101/2021.02.14.21251709
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