Article

Salience network atrophy links neuron type-specific pathobiology to loss of empathy in frontotemporal dementia

2019-07-03

Abstract excerpt

Each neurodegenerative syndrome reflects a stereotyped pattern of cellular, regional, and large-scale brain network degeneration. In behavioral variant frontotemporal dementia (bvFTD), a disorder of social-emotional function, von Economo neurons (VENs) and fork cells are among the initial neuronal targets. These large layer 5 projection neurons are concentrated in the anterior cingulate and frontoinsular (FI) cort...

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Literature Corpus work: 778aed74-65f3-5515-a409-5e0c6f154917
DOI: 10.1101/691212

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