Article

Bacterial metabolic signatures in MASLD predicted through gene-centric studies in stool metagenomes

2025-05-03

Abstract excerpt

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multifactorial condition influenced by the gut microbiome (GM). While previous studies have reported inconsistent associations between MASLD and key microbial clades using low-resolution 16S rRNA profiling, we employed high-resolution metagenomic sequencing and multi-marker taxonomic classification across three independent cohorts to identify ro...

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Literature Corpus work: 77803056-da23-510a-94e2-d7a3998f6347
DOI: 10.1101/2025.05.03.652020

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