Article
Moving beyond descriptive studies: harnessing metabolomics to elucidate the molecular mechanisms underpinning host-microbiome phenotypes.
Mucosal immunology - 1 Jun 2022
Bishop Stephanie L, Drikic Marija, Wacker Soren, Chen Yuan Yao, Kozyrskyj Anita L, Lewis Ian A
Abstract excerpt
Advances in technology and software have radically expanded the scope of metabolomics studies and allow us to monitor a broad transect of central carbon metabolism in routine studies. These increasingly sophisticated tools have shown that many human diseases are modulated by microbial metabolism. Despite this, it remains surprisingly difficult to move beyond these statistical associations and identify the...
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