Article

Systems Immunology Approaches to Understanding Immune Responses in Acute Infection of Yellow Fever Patients

2024-05-07

Abstract excerpt

<h4>Summary</h4> In the 2018 yellow fever (YF) outbreak in Brazil, we generated new transcriptomic data and combined it with clinical and immunological data to decode the pathogenesis of YF. Our analysis of 79 patients highlighted distinct gene expression patterns between acute YF infections, other viral infections, and the milder infection induced by the live-attenuated YF-17D vaccine. We identified a critical ro...

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Literature Corpus work: 77638eec-8dc1-55e9-914a-9925c11bce8a
DOI: 10.1101/2024.05.04.24306661

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