Article

Endogenous human stem cell-associated retroviruses

2015-08-10

Abstract excerpt

Recent discoveries of endogenous human stem cell-associated retroviruses (SCARs) revealed consistent activation of specific endogenous retroviral elements in human preimplantation embryos and documented the essential role of the sustained retroviral activities in the maintenance of pluripotency, functional identity and integrity of naïve-state embryonic stem cells, and anti-viral resistance of the early-stage huma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 772e9019-93b2-502f-9175-a5bb2217ca97
DOI: 10.1101/024273

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Endogenous human stem cell-associated retrovirusesDOI 10.1101/024273Read

Activation of endogenous human stem cell-associated retroviruses (SCARs) and therapy-resistant phenotypes of malignant tumors.Semantic proximity Read

Genomic and Molecular Maps of Stemness and Malignant Regulatory SignaturesSemantic proximity Read

Single cell genomics reveals activation signatures of endogenous SCAR's networks in aneuploid human embryos and clinically intractable malignant tumors.Semantic proximity Read

Human endogenous retroviruses and exogenous viral infectionsSemantic proximity Read

Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryoSemantic proximity Read

Classification and characterization of human endogenous retroviruses; mosaic forms are common.Semantic proximity Read

Human Endogenous Retroviruses Are Ancient Acquired Elements Still Shaping Innate Immune ResponsesSemantic proximity Read

Molecular diversity and phenotypic pleiotropy of ancient genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their contemporary impacts on pathophysiology of Modern Humans.Semantic proximity Read

HERVs and Cancer—A Comprehensive Review of the Relationship of Human Endogenous Retroviruses and Human CancersSemantic proximity Read

Contribution of Human Retroviruses to Disease Development—A Focus on the HIV– and HERV–Cancer Relationships and Treatment StrategiesSemantic proximity Read

Human endogenous retroviruses and cancerSemantic proximity Read

Human Endogenous Retroviruses in Health and Disease: A Symbiotic PerspectiveSemantic proximity Read