Article

PET is only moderately informative regarding theranostic Ttarget HIF-1α expression in solid tumors: A meta-analysis

2019-11-20

Abstract excerpt

<title>Abstract</title> <p>BACKGROUND: Hypoxia-inducible factor (HIF)-1α plays a key role in hypoxic adaptation of tumor cells. HIF-1α is overexpressed in solid tumor, directs the glucose metabolism pathway from oxidative to anaerobic pathway thereby reducing the oxygen consumption, decreases free radical level and thence prevents cancer cell death. 2-deoxy-2 [18F] fluoro-D-glucose (FDG) is taken up in solid tumo...

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Literature Corpus work: 76c9a761-820a-5906-b889-d0cbf07b4542
DOI: 10.21203/rs.2.17589/v1

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