Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota

30 Oct 2019

Abstract excerpt

To understand how antibiotic use affects the risk of a resistant infection, we present a computational model of the population dynamics of gut microbiota including antibiotic resistance-conferring plasmids. We then describe how this model is parameterized based on published microbiota data. Finally, we investigate how treatment history affects the prevalence of resistance among opportunistic enterobacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31666328
DOI: 10.1073/pnas.1912188116

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiotaPMID 31666328Read ↗

Quantifying antibiotic impact on within-host dynamics of extended-spectrum beta-lactamase resistance in hospitalized patientsSemantic proximity Read ↗

Antibiotic Treatment Drives the Diversification of the Human Gut ResistomeSemantic proximity Read ↗

Antibiotic Treatment Drives the Diversification of the Human Gut ResistomeSemantic proximity Read ↗

The Population Genetics of Antibiotic ResistanceSemantic proximity Read ↗

Quantifying antibiotic impact on within-patient dynamics of extended-spectrum beta-lactamase resistanceSemantic proximity Read ↗

Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiota in the Absence of Antibiotic TreatmentSemantic proximity Read ↗

Human gut mobileome during antibiotic therapy. A trajectory-based approach to analysis of the metagenomic time-series datasetsSemantic proximity Read ↗

Distinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort studySemantic proximity Read ↗

Host genetic and environmental factors shape the human gut resistomeSemantic proximity Read ↗

Longitudinal dynamics of gut plasmidome and antibiotic resistance during antibiotic therapy: a case reportSemantic proximity Read ↗

A modelling framework to characterize the impact of antibiotics on the gut microbiota diversitySemantic proximity Read ↗

Gut resistome development in healthy twin pairs in the first year of lifeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.