Article

Sex-dependent development of <i>Kras</i> -induced anal squamous cell carcinoma in mice

2021-08-06

Abstract excerpt

Anal squamous cell carcinoma (SCC) will be diagnosed in an estimated 9,080 adults in the United States this year, and rates have been rising over the last several decades. Most people that develop anal SCC have associated human papillomavirus (HPV) infection (∼85-95%), with approximately 5-15% of anal SCC cases occurring in HPV-negative patients from unknown etiology. This study identified and characterized a Kra...

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Literature Corpus work: 767e4546-ea31-57fb-845c-6f3d81c3bca0
DOI: 10.1101/2021.08.04.455138

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