Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cadmium Exposure Inhibits Branching Morphogenesis and Causes Alterations Consistent With HIF-1α Inhibition in Human Primary Breast Organoids

3 May 2018

Abstract excerpt

Developmental cadmium exposure in vivo disrupts mammary gland differentiation, while exposure of breast cell lines to cadmium causes invasion consistent with the epithelial-mesenchymal transition (EMT). The effects of cadmium on normal human breast stem cells have not been measured. Here, we quantified the effects of cadmium exposure on reduction mammoplasty patient-derived breast stem cell proliferation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Mesenchymal stem cell research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29741670
DOI: 10.1093/toxsci/kfy112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cadmium Exposure Inhibits Branching Morphogenesis and Causes Alterations Consistent With HIF-1α Inhibition in Human Primary Breast OrganoidsPMID 29741670Read ↗

Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoidsSemantic proximity Read ↗

Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells.Semantic proximity Read ↗

Cadmium promotes breast cancer cell proliferation, migration and invasion by inhibiting ACSS2/ATG5-mediated autophagySemantic proximity Read ↗

Chronic Exposure to Nanoplastics Alters Stem Cell Type-Specific Mechanisms, Promoting Cancer DevelopmentSemantic proximity Read ↗

Cadmium malignantly transforms normal human breast epithelial cells into a basal-like phenotype.Semantic proximity Read ↗

Single-Cell Multiome Impact of Prenatal Heavy Metal Exposure on Early Airway DevelopmentSemantic proximity Read ↗

Single-cell transcriptomics reveals a differential response of human bronchial epithelial cell-types to cadmium chlorideSemantic proximity Read ↗

High Throughput Transcriptomics to Understand Chemical Drivers of Aggressive Breast Cancer SubtypesSemantic proximity Read ↗

Alteration of Mammary Gland Development and Gene Expression by In Utero Exposure to CadmiumSemantic proximity Read ↗

Peroxidasin Enhances Basal Phenotype and Inhibits Branching Morphogenesis in Breast Epithelial Progenitor Cell Line D492.Semantic proximity Read ↗

Human-Relevant Lead Exposure During Differentiation Alters the Transcriptomic Profile of Human Induced Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read ↗

Human epithelial tooth organoids model disrupted amelogenesis following environmental and therapeutic exposuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.