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Article

Microbiopsy of living mouse brain for longitudinal molecular profiling

2026-01-24

Abstract excerpt

<h4>MOTIVATION</h4> Longitudinal molecular studies of the mouse brain are limited by the need for terminal tissue collection. This prevents analysis of preexisting molecular states and their evolution within the same individual. We developed a stereotactic microbiopsy technique that enables minimally invasive sampling of defined brain regions in vivo . The method preserves survival while yielding material suitab...

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Identifiers and source

Literature Corpus work
7665ae61-cd9a-54f1-b9c4-910dc1fe139e
DOI
10.64898/2026.01.22.701044
Open publication

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Microbiopsy of living mouse brain for longitudinal molecular profilingDOI 10.64898/2026.01.22.701044
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