Article
Identification and neuroprotective properties of NA-184, a selective calpain-2 inhibitor
2023-10-17
Abstract excerpt
Our laboratory has shown that calpain-2 activation in the brain following acute injury is directly related to neuronal damage and the long-term functional consequences of the injury, while calpain-1 activation is generally neuroprotective and calpain-1 deletion exacerbates neuronal injury. We have also shown that a relatively selective calpain-2 inhibitor, referred to as C2I, enhanced long-term potentiation and le...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 75f8a71e-a8c5-58e0-bd93-dcfc483094b1
- DOI
- 10.1101/2023.10.16.562509