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Marker-Free Chromosomal Engineering of <em>Lactococcus lactis</em> for <em>Streptococcus agalactiae</em> Surface Immunogenic Protein Delivery: Toward Probiotic-Based Mucosal Biomedicine

2026-06-05

Abstract excerpt

Food-grade lactic acid bacteria are increasingly recognized as promising candidates for mucosal immunization and various health applications. However, plasmid-based expression systems often face challenges related to antibiotic-resistance markers and genetic instability. To address these limitations, we developed and microbiologically characterized a marker-free strain of Lactococcus lactis subsp. cremoris NZ9000....

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Literature Corpus work
75e480f2-94ca-5fb2-a101-aae16e92afa5
DOI
10.20944/preprints202606.0477.v1
Open publication

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Marker-Free Chromosomal Engineering of <em>Lactococcus lactis</em> for <em>Streptococcus agalactiae</em> Surface Immunogenic Protein Delivery: Toward Probiotic-Based Mucosal BiomedicineDOI 10.20944/preprints202606.0477.v1
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