Article

Master Transcription Factors Regulate the DNA Methylation Landscape During Hepatocyte Differentiation

2020-12-17

Abstract excerpt

<h4>Background</h4> Hepatocytes are the dominant cell type of the human liver, with functions in metabolism, detoxification, and in producing secreted proteins. During the process of hepatocyte differentiation, gene regulation and master transcription factors have been extensively investigated, whereas little is known about how the epigenome is regulated, particularly the dynamics of DNA methylation, and the upst...

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Literature Corpus work: 75db2550-7846-5589-8a91-72ccb03cd4e6
DOI: 10.1101/2020.12.16.423165

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