Article

Biological Database Mining for LLM-Driven Alzheimer’s Disease Drug Repurposing

2024-12-08

Abstract excerpt

<h4>BACKGROUND</h4> This study presents a software pipeline that leverages LLMs to apply knowledge stored in natural language (such as in pharmacological texts) and ontologies in a transparent Drug Repurposing (DR) information structure. <h4>METHODS</h4> Alzheimer’s Disease (AD) related entries in Gene Ontology and DrugBank were integrated into a Knowledge Graph database to inform LLM prompts. 16,581 drugs were...

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Literature Corpus work: 75d2ed84-4b68-5921-a897-5aba7931bbc1
DOI: 10.1101/2024.12.04.626255

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