Article

Retrieval-Augmented Generative AI Versus Human-Curated Expert Systems in Drug-Drug Interaction Screening

2026-05-27

Abstract excerpt

<h4>Background: </h4> Clinical decision support systems are integral components of modern healthcare information technology, aiming to enhance medication safety by identifying potential drug–drug interactions (DDIs). Traditional expert-curated databases, such as LexiDrug, provide structured interaction data but may vary in coverage and clinical recommendations. Meanwhile, retrieval-augmented generative artificial...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2b794d67-59f8-596a-b7f2-104a5d9b8743
DOI: 10.20944/preprints202605.1786.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Retrieval-Augmented Generative AI Versus Human-Curated Expert Systems in Drug-Drug Interaction ScreeningDOI 10.20944/preprints202605.1786.v1Read

DrugReX: an explainable drug repurposing system powered by large language models and literature-based knowledge graphSemantic proximity Read

Development and validation of a generative AI-assisted medication-indication knowledge baseSemantic proximity Read

Will generative AI help solve systematic literature reviews? Evidence from a 2-year research programmeSemantic proximity Read

Development and Testing of a Novel Large Language Model-Based Clinical Decision Support Systems for Medication Safety in 12 Clinical SpecialtiesSemantic proximity Read

Bridging AI and Healthcare: A Scoping Review of Retrieval-Augmented Generation—Ethics, Bias, Transparency, Improvements, and ApplicationsSemantic proximity Read

dgiLIT: A Method for Prioritization and AI Curation of Drug-Gene InteractionsSemantic proximity Read

Comparing Physicians’ Assessments of Context-specific AI-powered clinical reasoning assistant with General-Purpose AI agent: A Prospective Multi-Site Physician Evaluation of VITA versus ChatGPT in India and BangladeshSemantic proximity Read

A framework for human-artificial intelligence co-learning for disease activity labeling using electronic health recordsSemantic proximity Read

Dual Inference Routes for Natural Language Hypothesis Generation in Multimodal Drug Discovery: An Early Experimentation StudySemantic proximity Read

Multisite Real-World Validation of an Electronic Health Record-Integrated Generative Artificial Intelligence Tool for Venous Thromboembolism Risk StratificationSemantic proximity Read

Empowering Personalized Pharmacogenomics with Generative AI SolutionsSemantic proximity Read

Biological Database Mining for LLM-Driven Alzheimer’s Disease Drug RepurposingSemantic proximity Read