Article

Engineering RNA viruses with unnatural amino acid to evoke adjustable immune response in mice

2021-12-07

Abstract excerpt

Ribonucleic acid (RNA) viruses pose heavy burdens on public-health systems. Synthetic biology holds great potential for artificially controlling their replication, a strategy that could be used to attenuate infectious viruses but is still in the exploratory stage. Herein, we used the genetic-code expansion technique to convert Enterovirus 71 (EV71), a model of RNA virus, into a controllable EV71 strain carrying t...

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Literature Corpus work: 75d26f31-f7a5-55ff-a10b-e2255216aeeb
DOI: 10.1101/2021.12.04.471206

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